Hypogammaglobulinaemia

Recurring infections that seem to never fully resolve can leave you feeling constantly run down and worried about your immune system’s ability to protect you. Hypogammaglobulinemia weakens your body’s defense system by reducing the antibodies needed to fight off bacteria, viruses, and other threats. When oral antibiotics and standard treatments aren’t enough to keep infections at bay, Bioinfusion Center offers immune globulin replacement therapy to restore your antibody levels. Cindy Crosby, MSN, FNP, CCRN, CRNI, and the medical team provide this essential treatment to help rebuild your immune defenses. Call the Farmington Hills,

What is hypogammaglobulinemia?

Hypogammaglobulinemia means your body doesn’t produce enough immunoglobulins — the antibodies that recognize and neutralize harmful bacteria, viruses, and other pathogens. Without adequate antibody levels, your immune system struggles to defend against infections.

This condition can be primary, meaning you’re born with it, or secondary, developing later due to certain medications, cancers, or other medical treatments that suppress antibody production. Either way, you can experience frequent, severe, or prolonged infections that your body can’t clear on its own.

What types of infections occur with hypogammaglobulinemia?

People with hypogammaglobulinemia typically experience recurrent infections affecting areas like:

• Respiratory tract infections like pneumonia, bronchitis, and sinus infections
• Gastrointestinal infections causing chronic diarrhea
• Skin and soft tissue infections that heal slowly
• Ear infections that become chronic or keep returning

These infections often resist standard antibiotic treatment or require multiple courses to clear completely. Many people experience one illness after another with little recovery time between episodes, making it difficult to maintain normalcy.

When should you consider immune globulin replacement therapy for hypogammaglobulinemia?

Consider testing your immunoglobulin levels if you experience:

• More than four respiratory infections per year 
• Simple colds that often turn into pneumonia or bronchitis
• Sinus infections requiring multiple antibiotic courses
• Ear infections that never completely clear 
• Cuts or minor wounds that take weeks to heal 
• Hospitalizations for infections that most people recover from at home
• Unusual infections from bacteria that typically don’t cause problems 
• Serious complications from common infections 

Many people also notice they catch every illness that goes around their workplace or family, experiencing little recovery time between infections.

How does immune globulin therapy for hypogammaglobulinemia work?

Bioinfusion Center provides immune globulin replacement therapy to replace the missing antibodies your body isn’t producing effectively. Here’s how it works:

Gamunex-C, Gammagard, and Octagam 

These immune globulin products contain a range of antibodies against common pathogens. You typically receive infusions every 3-4 weeks, depending on your specific antibody levels and infection patterns. The treatment helps restore your immune system’s ability to recognize and fight infections.

The team monitors your antibody levels throughout treatment and adjusts infusion timing based on how your body processes the replacement antibodies and your individual infection patterns.

Call Bioinfusion Center today to discuss whether immune globulin replacement therapy could help strengthen your immune defenses and reduce recurring infections.