Ulcerative Colitis

Ulcerative colitis affects nearly 900,000 Americans with chronic inflammation that can completely disrupt their daily routine and long-term health. This autoimmune condition creates ongoing damage in your colon that oral medications often struggle to control effectively. Bioinfusion Center offers proven biologic therapies, including Entyvio®, Stelara®, and Remicade®, that target the root causes of your inflammation. Cindy Crosby, MSN, FNP, CCRN, CRNI, and the medical team provide these advanced treatments with the expertise you need for better disease control. Call the Farmington Hills, Michigan, office today to learn about biologic therapy for ulcerative colitis or book a consultation online.

What is ulcerative colitis?

Ulcerative colitis is your immune system attacking your colon lining. The inflammation starts in your rectum and can spread upward through your large intestine, creating ulcers and bleeding that make normal bathroom habits impossible.

People with ulcerative colitis often experience: 

• Bloody diarrhea
• Urgent bathroom trips
• Severe stomach cramping
• Fatigue 
• Weight loss
• Fever

Unlike Crohn’s disease, which affects random areas throughout your digestive tract, ulcerative colitis creates one continuous stretch of inflamed, damaged tissue in your colon.

What triggers ulcerative colitis flares?

Your family history matters most. Having relatives with inflammatory bowel disease increases your risk considerably, though many people with the genetic tendency never develop symptoms.

Common triggers that can spark flares include:

• Stress from major life changes or ongoing pressure
• Infections that disrupt your gut bacteria balance
• Certain medications like anti-inflammatory pain medication or antibiotics
• Dietary changes, though specific food triggers vary between people

The exact cause remains unclear, but it likely involves a combination of genetics, immune system dysfunction, and environmental factors working together.

Can biologic therapy help control ulcerative colitis?

Standard treatments like steroids help initially but often stop working or cause serious side effects with long-term use. Biologic infusions target the specific proteins driving your inflammation instead of just suppressing your entire immune system.

Bioinfusion Center offers several proven biologics, each working through different pathways to give you the best chance at lasting remission.

What ulcerative colitis biologics do you provide?

The team at Bioinfusion Center offers several biologic medications targeting colon inflammation, including:

Entyvio® (vedolizumab) 

Entyvio is a gut-selective biologic, which means it doesn’t weaken your overall immune system like some other biologics. During treatment, you receive infusions every eight weeks after completing the initial loading doses, and most people see symptom improvement within six weeks.

Remicade® (infliximab) 

Remicade blocks TNF-alpha, a protein that drives inflammation throughout your colon. Expect to get infusions every eight weeks in a monitored clinic setting, where the team tracks your response and adjusts treatment as needed.

Stelara® (ustekinumab) 

Stelara targets interleukin proteins that fuel intestinal inflammation. You start with an intravenous (IV) infusion at Bioinfusion Center, then switch to self-injections every 8-12 weeks at home. 

Call Bioinfusion Center today to discuss how targeted biologic therapy could help you take control of your ulcerative colitis.